Sox2 tumor

Determine the promoter occupancies of Soxin the MCFRU and RR breast cancer cell populations. In lung development, Soxcontrols the branching morphogenesis of the bronchial tree and differentiation of the. And medulloblastoma tumor in vitro and in vivo using microarray analysis.

The SOXprotein activates the genes that cause neural progenitor cells to turn. To date, studies have shown SOXto be amplified in. SOX(SRY (sex determining region Y)-box 2) Expression, SOXis overexpressed in stem cells and many different kinds of cancer cells, including glioma, breast cancer, colorectal cancer and etc.

The potential role of SOXin the anti-apoptosis property of cancer. Soxexpression in brain tumors: a reflection of the neuroglial differentiation pathway. Discovery of new role of SOXprotein sheds light on neurogenesis.

SOX2: A Glioma-Specific Marker and a Potential Target for Therapy

SoxHolds the Key to Lung Cancer Susceptibility Science Signaling Some cells respond to oncogenic mutations by becoming cancerous and others do not. SOXwas reported to promote metastasis in various tumor tissues however the underlying mechanisms remain elusive. Heterogeneity within tumors is becoming increasingly recognized as an important cause of treatment failure in cancer.

The role of SOXin small cell lung cancer, lung adenocarcinoma. SOXcontrols tumour initiation and cancer stem-cell functions in). SOXand cancer: current research and its implications in the clinic. SOXsilencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of).

SOX- , the free encyclopedia Canceredit. SOXsilencing in glioblastoma tumor-initiating cells causes stop of. SOXcontrols tumour initiation and cancer stem-cell functions in. We validated our findings with conventional chromatin.

To identify novel proteins essential for the fate of brain tumor cells, we examined the protein interaction network of the transcription factor, SOX2. SOXexpression correlates with lymph-node metastases and. Soxis required to maintain cancer stem cells in a mouse model of. SOX2: A Glioma-Specific Marker and a Potential Target for Therapy. For example, in mice, when all cells of the lung contain a cancer-causing.

SOXGene - GeneCards SOXProtein SOXAntibody SOX(SRY (Sex Determining Region Y)-Box 2) is a Protein Coding gene. The PRKCI and SOXOncogenes Are Coamplified and.

Profiling gene promoter occupancy of Soxin two phenotypically. Cooperate to Activate Hedgehog Signaling in Lung Squamous Cell. Design: We analyzed 1glial tumors and non-glial primary CNS tumors by immunohistochemistry for expression of SOXprotein. The SOX2-Interactome in Brain Cancer Cells Identifies the. Therapies that target SOXactivity in cancer stem cells offer.

Soxis required to maintain cancer stem cells in a mouse). Recent studies have revealed ectopic expression of SOXin a number of cancer types and disclosed vital contributions of SOXto the stemness property of. Particularly, the role of SOXin cancer pathogenesis has become of interest in the field.

Soxexpression in brain tumors: a reflection of the neuroglial. SOXpromotes tumor metastasis by stimulating epithelial-to.

SOX- , the free encyclopedia

Sox a marker for stem-like tumor cells in skin squamous cell. The PRKCI and SOXOncogenes Are Coamplified and Cooperate. Transcriptional profiling of SOX2-GFP-expressing CSCs and of tumour epithelial cells upon Soxdeletion uncovered a gene network regulated.

Overexpression of SOXhas been described in all types of lung cancer tissues, including small cell and squamous cell carcinoma but also adenocarcinoma. SOXexpression correlates with lymph-node metastases and distant spread in right-sided colon cancer. Aciclovir - effektives Mittel gegen Herpes 20. Adrenal cortical carcinoma: vimentin strongly positive, cytokeratin weakly positive, synaptophysin weakly positive, chromogranin negative (Am). Bitte ben Sie uns zu einem späteren Zeitpunkt wieder.

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